Will a 4L60E bolt up to an LQ4 6.0, and will it survive behind it?

Bolting up: yes, it's the same GM LS bellhousing pattern. Use an LS-version 4L60E (300 mm input shaft and LS converter) with the LS 4L60E flexplate, which has the 11.062 in converter pattern. Exception: some 1999–2000 LQ4s have the long crank flange, and they have no easy fix for a 4L60E or 700R4 — the practical option is a 2001-or-newer 6.0 crank. See why early LQ4s need a different flexplate.

Surviving: the LQ4 makes about 355–375 lb-ft stock, which is at or above a stock 4L60E's 300–360 lb-ft range. GM itself introduced the stronger 4L65E (up to 380 lb-ft) in 2001 for the 6.0 Vortec. A stock 4L60E behind a stock LQ4 in a light vehicle is at its limit; with towing, weight or power added, build it or use a 4L65E or 4L80E.

	Torque it's built for	Notes
4L60E, stock	about 300–360 lb-ft (≈300–400 hp in a typical street car)	Wikipedia lists a 360 lb-ft rating; about 133 lb dry
4L65E, stock	up to 380 lb-ft	Stronger planetaries and an extra 3–4 clutch; from 2001 behind the 6.0 Vortec
4L60E, built street unit	≈450–500 hp	Upgraded 3–4 pack, input shaft, sun shell, valve body
4L80E, stock	440 lb-ft	Heavier-duty truck unit, rated to 18,000 lb GVWR (axle/vehicle dependent)